Search results for " Aurora A kinase"

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Immunohistochemical/histochemical double staining method in the study of the columnar metaplasia of the oesophagus

2014

Intestinal metaplasia in Barrett’s oesophagus (BO) represents an important risk factor for oesophageal adenocarcinoma. Instead, few and controversial data are reported about the progression risk of columnar-lined oesophagus without intestinal metaplasia (CLO), posing an issue about its clinical management. The aim was to evaluate if some immunophenotypic changes were present in CLO independently of the presence of the goblet cells. We studied a series of oesophageal biopsies from patients with endoscopic finding of columnar metaplasia, by performing some immunohistochemical stainings (CK7, p53, AuroraA) combined with histochemistry (Alcian-blue and Alcian/PAS), with the aim of simultaneousl…

Mild Dysplasiap53MalePathologymedicine.medical_specialtyHistologyEsophageal NeoplasmsBiophysicsSettore MED/08 - Anatomia PatologicaBiologyAdenocarcinomadigestive systemBarrett EsophagusEsophagusAntigenMetaplasiamedicineHumansEsophaguslcsh:QH301-705.5Retrospective StudiesMetaplasiaStaining and LabelingBrief ReportBarrett’s oesophagusIntestinal metaplasiaCell Biologymedicine.diseaseImmunohistochemistryEpitheliumdigestive system diseasesBarrett’s oesophagus columnar-lined oesophagus p53 Aurora A kinasemedicine.anatomical_structureBarrett’s oesophagus columnar-lined oesophagus p53 Aurora A kinase.lcsh:Biology (General)columnar-lined oesophagusAdenocarcinomaImmunohistochemistryAurora A kinaseFemaleGoblet Cellsmedicine.symptomEuropean Journal of Histochemistry

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